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The BioTrans 2019 symposium showcased recent advances in biocatalysis research, covering various cutting edge topics in the field, from reprogramming synthetic biology and redesign of natural enzymes to development of new (chemo)enzymatic cascades and novel classes of artificial enzymes . The symposium included invited lectures from experimentalists and theoreticians, from both academia and industry. The invited speakers are all current or emerging leaders in their respective sub-fields, and bring together the interface between chemistry and biology. The combination of these speakers in one symposium provides an exceptional opportunity to bridge disciplines and engage in active discussion, while maintaining a strong link to both academic and industrial applications. Except for various lectures by invited experts in the field, the program will include oral presentations (selected based on submitted abstracts), poster pitch talks and posters. Due to the interdisciplinary nature of the topic, high-quality abstracts from any area related to the topic of the symposium, including synthetic and evolutionary biology, genetics, biomolecular engineering, protein biochemistry, computational chemistry and synthetic (bio)organic chemistry were welcomed.