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First organized by hemostasis pioneers Earl W. Davie and Oscar Ratnoff in 1973, the Hemostasis Gordon Research Conference (GRC) is considered the premiere small-format scientific meeting on the topics of blood coagulation, platelet biology, anticoagulant pathways and associated diseases. The Hemostasis GRC brings together scientists interested in the biology, biochemistry and genetics of platelets and coagulation proteins - including the myriad roles these proteins play beyond hemostasis; physicians involved in the treatment of bleeding and thrombotic diseases; and investigators from small and large pharmaceutical/biotechnology companies developing new therapeutics and diagnostics for disorders of the hemostatic system. The 2016 Hemostasis GRC will be held July 24-29 at Stoweflake Mountain Resort and Conference Center in Stowe, Vermont - only 36 miles from Burlington International Airport. The conference site provides a comfortable and inviting location for all participants surrounded by the Green Mountains, including a Pinnacle Award Conference Center and over 40,000 square feet of highly functional space for indoor and outdoor activities. Numerous recreational activities are available to participants including horseback riding, biking, hiking, golf, tennis, boating, and swimming. A primary goal of the conference is for nearly every attendee to participate actively either as a speaker, discussion leader, or poster presenter. Held before dinner on four days of the conference, the poster sessions are always well attended and provide a dedicated forum for interaction among junior and senior investigators in the field. Afternoons are open for informal discussion among attendees and leisure activities that enhance interactions, intellectual exchange, and foster new collaborations—a traditional and unique component of the Hemostasis GRC. All applicants who are not invited speakers or discussion leaders are encouraged to submit an abstract for presentation at one of the four scheduled poster sessions and consideration for an oral presentation at the Late-Breaking Topics session.