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This Symposium is dedicated to the emerging challenges and opportunities for in silico drug discovery. The Symposium's main topics: development and practical application of computational methods for finding and validation of new pharmacological targets, in silico design of potent and safe pharmaceutical agents, optimization of the structure and properties of drug-like compounds, rational approaches to the utilization of pharmacotherapeutic remedies in medical practice. This information will be useful for researchers whose investigations are dedicated to creating computational methods and their application to drug research and development using bio- and chemoinformatics methods based on post-genomic technologies. It can also be useful for undergraduate, graduate, and postgraduate students specializing in the relevant fields