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Tailoring of morphology and surface properties of porous silicon nanoparticles as contrast agents in magnetic resonance imaging for biomedical applicationsдоклад на конференции
- Авторы: Perepukhov A.M., Gippius A.A., Minnekhanov A.A., Zvereva E.A., Kargina* Yu V., Timoshenko V.Yu, Maximychev A.V., Osmin-kina L.A., Gulyaev M.V., Pirogov Yu A., Gongalsky M.B.
- Международная Конференция : Porous Semiconductors - Science and Technology PSST 2018
- Даты проведения конференции: 10-17 марта 2018
- Дата доклада: 13 марта 2018
- Тип доклада: Стендовый
- Докладчик: Kargina* Yu V.
- Место проведения: Ла Гранде Мотте, France
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Аннотация доклада:
Porous silicon (PSi) nanoparticles (NPs) with various morphology and surface conditioning were explored as contrast agents (CAs) in magnetic resonance imaging (MRI) by analyzing the longitudinal and transverse relaxation times of protons in water. The transverse relaxation rate was found to be controlled by both the morphology and paramagnetic center concentration. The obtained results revealed stronger shortening of the transverse relaxation caused by microporous PSi NPs, which were subjected to thermal annealing in vacuum resulting in the defect density of the order of 10^17 g^-1. The obtained results indicate prospective pathways for the engineering of PSi NPs based CAs for MRI applications.
- Добавил в систему: Каргина Юлия Валерьевна