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Introduction. Today a model of cold and hot cognition which opens up new opportunities for investigating the mechanisms of violations in depressive disorders actively develops. The description of these two systems promotes an understanding of interaction between the cognitive and affective spheres. However, at the present time there is no neuropsychological battery, which helps to conduct a comprehensive study of the cognitive-affective sphere in patients with affective disorders. Objective. Elaboration and adaptation of a complex of neuropsychological tests comprised of emotionally loaded material. Aims. Description of neurocognitive symptoms and their division into cold and hot violations with the designation of their brain and psychological mechanisms. Methods. 33 patients diagnosed with depression according to ICD-10 (F31.3, F31.4, F31.5, F32.1, F33.1, F33.2, F34.0, F34.1), 14 males and 19 females, aged 33±16, disease duration 13±12 years, and 33 healthy controls, 17 males and 16 females, aged 36,5±15,5. Standardized neuropsychological tests and tests base on emotiogenic stimuli were administered. Results. There is a neurocognitive deficit in patients with affective disorders manifested in changes of a psychomotor speed and the work of number cognitive functions. These patients demonstrate a decreased attention to negative stimuli combined with a decreased attention to positive stimuli. Conclusion. Patients with depressive disorders are more prone to distortion of cognitive activity in emotiogenic conditions. The abnormal processes of hot cognition in these patients conceptualize such a core symptom of depression as anhedonia, which is a probable endophenotype of depression.