ИСТИНА

End-stage renal disease (ESRD) patients have severely elevated risk of cardiovascular disease. Arterial stiffness is a principal pathogenetic mechanism of aortic systolic blood pressure (SBP) augmentation, left ventricular hypertrophy and sudden cardiac death. The aim of the study was to evaluate the association between parameters of pulse wave and 44-hour ambulatory blood pressure (ABP) variables. In 68 patients with ESRD on maintenance hemodialysis applanation tonometry and 44-hour ABP monitoring was performed. Mann-Whitney test was considered significant if p<0.05. Carotid-femoral pulse wave velocity (PWV) ≥ 10 m/s was revealed in 16 (23,5%) patients. Patients with PWV ≥ 10 vs < 10 m/s had higher dialysis duration, peripheral SBP, peripheral diastolic blood pressure (PDBP), 44-hour heart rate (HR), mean day one HR, 44-hour DBPV, day two SBP variability, mean day two BD. Patients with PWV ≥ 10 vs < 10 m/s had lower daytime diastolic BP variability (DBPV), day one.