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We study the production of prompt photons at high energy in the framework of the kT-factorization approach. The amplitude for production of a single photon associated with quark pair in the fusion of two off-shell gluons is calculated. We used the unintegrated gluon distributions in a proton which were obtained from the full CCFM evolution equation as well as from the Kimber-Martin-Ryskin prescription. Theoretical results are compared with recent experimental data taken by the D0 and CDF collaborat ions at Tevatron.