ИСТИНА

Background and aims. Epidemiological monitoring of diabetes mellitus (DM) in Russian Federation (RF) founded since 1996 through the national diabetes registry, carried on online format since 2014. Nowadays it works as the unified dynamic database that provide DM data from the whole country. The aim of our study was to access the prevalence and dynamics of DM and diabetes-related complications during the last decade 2007-2019 yr. Materials and methods: The object of the study analysis was the depersonalized database of the national diabetes registry of RF with more than 4630 clinics of primary care data (uploaded until 01/01/2020). Results: The total number of registered DM patients in RF at 01.01.2020 was 4752585 (3,2% of the population), including 261 thousand patients with type 1 (T1), 4,4 million with type 2 (T2) and 96,5 thousand with other DM types, that reflects the growth in 2,3 times since 2000 yr, with annual increase by 250-320 thousand patients. There were about 11 and 315 thousands of new cases in T1 and T2 patients revealed, respectively. Gender distribution M/F in T1: 54/46%; in T2: 29,7/70,3%. The current HbA1c reported annually in 59% and 52% of patients with T1 and T2, respectively, with proportion of patients reached the target level <7% in 2019: T1 - 35,5%: T2 - 52,3%. Data of complications prevalence in 2019 among T1/T2 patients were: for diabetic retinopathy (DR) 31,4%/ 13,5%; chronic kidney disease (CKD) – 23,2%/15,1%, neuropathy 42,5%/23,5%; diabetic foot (DF) – 3,5%/1,6%; amputations – 1,1%/0,7%; myocardial infarction (MI) – 1%/3,3%, CHD – 2,7%/10,1%. We observed decrease in the frequencies of diabetes-related complications compared with 2007 year in T1/T2 patients, respectively: ketoacidotic coma in 1,7/3,3 times, blindness in 2,5/4,6, DF in 1,8/3,2 times, CKD in 1,4/1,2 times, MI in 5,7/2,3 times, cerebrovascular disease in 3,8/1,9 times (see the graph). Conclusions: Despite the continued increase in the number of DM patients, significant achievements have been made in the management of diabetes in RF over the past decade. There is a significant improvement in the quality of diagnostics and decrease of complications frequency. The priority remains the development of specialized diabetes care to standardization of screening algorithms and the early methods of diagnostics.