![]() |
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ЦЭМИ РАН |
||
Typical MR scanners are focused on the detection of proton (1H). Detectionof other nuclei provides additional diagnostic information – about the state oftissues, cellular processes, etc. Sodium is of considerable interest – the naturalabundance of the 23Na isotope is 100%, and the gyromagnetic ratio is 3.8times lower than of proton. However, the sodium content in living tissues is2-3 orders of magnitude lower than that of hydrogen, which determines the lowsensitivity of the method. The detection of fluorine signals is also of interest inMRI. The 19F isotope has 100% natural abundance and its gyromagnetic ratio isonly 6% less than of proton. So, 1H and 19F MRI are comparable in sensitivity.The content of fluorine in living tissues is extremely low, therefore, it is veryproductive to detect signals from fluorine-containing substance injected into thebody, for example, a drug, as well as from gases in the lungs, since there is nobackground from normal tissues in the images. The use of strong fields – from3 T and more increases the sensitivity of multinuclear methods. However, suchfields are unattainable with open-type magnets and compact portable MRI systems.Therefore, it is of interest to evaluate the productivity of multinuclear researchon low-field equipment. We carried out these studies on a 0.5T clinical scannerBruker Tomikon S50 (1H NMR frequency is 21.1 MHz). The technical reworkconcerned only the coils, which were used as modified proprietary prototypes,originally intended for the detection of protons.
№ | Имя | Описание | Имя файла | Размер | Добавлен |
---|---|---|---|---|---|
1. | Полный текст | Stranitsyi_iz_Book_of_abstracts_MDMR.2021_.pdf | 334,6 КБ | 8 апреля 2022 [nico-06-11] | |
2. | Иллюстрация | Arina-kazan-2021.jpg | 222,6 КБ | 16 ноября 2021 [nico-06-11] | |
3. | Иллюстрация | Poster_Award.pdf | 1,4 МБ | 19 ноября 2021 [tarasova_arina] |