ИСТИНА

Coenzyme Q10 (CoQ10) plays an important role in the generation of the cell energy – ATP, being part of the electron transport chain in process of oxidative phosphorylation in the internal membrane of mitochondria. Many diseases of the cardiovascular system and congestive heart failure, in particular, depend on decreased content of Coq10 and myocardial CoQ10 content tends to decline as the degree of heart failure worsens. Additionally, CoQ10, through its antioxidant effects, may reduce oxidative stress, which is known to adversely affect left ventricular ejection fraction and alter disease outcomes. The long­term supplementation of CoQ10 in patients with HF seems safe, appears to produce symptomatic improvements, and, more importantly, has been found to significantly reduce major adverse cardiovascular events and mortality. Ubiquinol is the reduced form of coenzyme Q10. This drug is expected to complement coenzyme Q10, which is naturally found in the organism, helping the cells to produce more energy and thus relieve the symptoms of this disease.