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Brain tumors and treatment after causes delayed consequences that negatively affect the quality of a children’s life: timing, working memory, intelligence, attention, sensorimotor functions, cognitive flexibility and other mental functions (Puhr et al., 2019). Besides, cancer patients often complain of chronically fatigue, both physical and cognitive, and emotional overload before and during treatment and after its completion (Schmidt et al., 2020). The study aimed to identify some characteristics of cancer-related fatigue in children under dynamic observation after the completion of brain tumor treatment. The sample consisted of 67 school-age children (36 girls, 12.7±2.9 years old, and 31 boys, 13.1±3.05 years old) under dynamic observation for 5-139 months after the treatment was over. The "The Turkish Scale for the Assessment of Fatigue in Pediatric Oncology Patients Aged 7-18" adapted for the Russian-speaking audience (Deviaterikova et al., 2021) was used to measure fatigue symptoms, experienced by the child, according to subscales: "Fatigue associated with daily activities", "Subjective feeling of fatigue", "Sleep related fatigue". Maximal tapping test was used to measure nervous system endurance. The feeling of fatigue persists in children even after the completion of treatment for brain tumor, both according to the patients themselves and to their parents’ point of view. Older children and their parents more often complain of chronic fatigue, which may be a consequence and increased reflection and responsibility. Children with more severe fatigue symptoms demonstrated more pronounced slowdown of tapping frequency from the beginning to the end of 30-seconds test. Unexpectedly, parents notice sleep problems associated with fatigue in children who gradually increase their speed in the tapping test. Maximal tapping dynamics can be potentially applied as an objective measure of subjective fatigue in cancer patients.