ИСТИНА

Coilin is a major scaffold protein of the Cajal bodies, the subnuclear structures which are physically and functionally associated with the nucleolus. Coilin provides functions for the formation and operation of Cajal bodies which are involved in various biological processes including metabolism RNAs and RNPs. Fibrillarin is one of the major proteins of the nucleolus. It plays essential role in ribosome biogenesis including pre-rRNA processing and methylation of rRNA and snRNAs.In the present study we investigatedthe role of coilin and fibrillarin inabiotic stressresponses.