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EXPRESSION ANALYSIS OF ANTIVIRAL PATTERN-RECOGNITION RECEPTORS IN PLACENTA VILLI & MYOMETRIUM IN CASES OF SEVERE PREECLAMPSIAдоклад на конференции
- Авторы: Baev O.R., Nizyaeva N.V., Shchegolev A.I., Khlestova G.V., Nagovitsyna M.N., Kulikova G.V.
- Международная Конференция (Конгресс) : Maternal fetal neonatal medicine
- Даты проведения конференции: 24-26 апреля 2017
- Дата доклада: 24 апреля 2017
- Тип доклада: Стендовый
- Докладчик: не указан
- Место проведения: Лондон, United Kingdom
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Аннотация доклада:
Preeclampsia (PE) is a complication of pregnancy characterized by proteinuria (>0,3 g/day) and hypertension (140/90 mm Hg). The placenta protects the fetus from viruses and bacteria mainly by means of factors of non-specific resistance and innate immunity such as pattern-recognition receptors: NOD-like and TLR-like receptors. However there are typically immune tolerance disturbances in women with preeclampsia, but the role of antiviral protection receptors (NOD-1, TLR9) is still unknown. Besides to viral derivatives a few literature data suggests fetal DNA may serve as TLR9 ligand.
- Добавил в систему: Хлестова Галина Владимировна