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Invention refers to pharmaceutical industry, particularly a prolonged-release medicated film. The prolonged-release medicated film containing a drug substance, gelatin in the form of 30% water solution, glycerol, methyl cellulose in the form of 5% water solution, agar-agar in the form of 30% water solution, and 40% ethanol taken in certain proportions. A method for preparing the prolonged-release medicated film. A method for applying the prolonged-release medicated film. EFFECT: medicated film is dissolved for 3 days and gradually releases an active ingredient; the film is areactogenic, keeps cell cooperation in a wound and promotes fusion of the wound edges