In vitro mineralization of silicon containing calcium phosphate bioceramicsстатья
Статья опубликована в высокорейтинговом журнале
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Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:In vitro mineralization of silicon containing calcium phosphate (Si-CaP) bioceramics was investigated in the constant-composition double-diffusion (CCDD) device under physiological conditions. The experiments were performed with porous pellets made of Si-CaP, which was synthesized from Ca(NO3)(2).4H(2)O, NH4H2PO4, ammonia and fumed silica according to a newly developed single-stage preparation route. Twice as condensed aqueous solutions of the Kokubo's revised simulated body fluid (rSBF) were used as mineralizing medium. All samples of Si-CaP bioceramics possessed excellent in vitro mineralizing properties and, therefore, this material is ready for further trials with cells. Simultaneously, the workability of the CCDD device in a less condensed (twofold instead of the previously used fourfold) aqueous solutions of rSBF was confirmed.