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Role of Restriction–Modification Systems in Prokaryotic Evolution and Ecologyстатья Перевод
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 7 ноября 2015 г.
- Авторы: Ershova A.S., Rusinov I.S., Spirin S.A., Karyagina A.S., Alexeevski A.V.
- Журнал: Biochemistry (Moscow)
- Том: 80
- Номер: 10
- Год издания: 2015
- Издательство: Pleiades Publishing, Ltd
- Местоположение издательства: Road Town, United Kingdom
- Первая страница: 1373
- Последняя страница: 1386
- DOI: 10.1134/S0006297915100193
- Аннотация: Restriction–modification (R M) systems are able to methylate or cleave DNA depending on methylation status of their recognition site. It allows them to protect bacterial cells from invasion by foreign DNA. Comparative analysis of a large number of available bacterial genomes and methylomes clearly demonstrates that the role of R M systems in bacteria is wider than only defense. R M systems maintain heterogeneity of a bacterial population and are involved in adaptation of bacteria to change in their environmental conditions. R M systems can be essential for host colonization by pathogenic bacteria. Phase variation and intragenomic recombinations are sources of the fast evolution of the specificity of R M systems.This review focuses on the influence of R M systems on evolution and ecology of prokaryotes.
- Добавил в систему: Алексеевский Андрей Владимирович