The Prospects of Using Transgenic Insects in Biological Programsстатья
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Дата последнего поиска статьи во внешних источниках: 19 ноября 2018 г.
Аннотация:Methods of biocontrol are widely used for suppression of pests and human disease vectors. One of
the key methods is insects sterilization (sterile insect technique – SIT), which currently is accomplished by
irradiation. Radiationexposed insects have reduced fitness so theis competitive abilities are diminished as
compared to insects from wild populations. Modern bioengineering is capable of producing transgenic
insects with predetermined traits, and by now the schemes for getting sterile insects without exposure to radi
ation are developed. Another area of modern studies is producing insects that are unable to transmit diseases
malaria, for example. In the present review the implementation and perspectives are outlined for replacement
of Anopheles wild populations with transgenic mosquitos. The main way for delivering the genetic material to
recipient’s genome is using transposonbased constructs. The markers of transgenesis are described. The
potential danger for the environment of transgenic constructs remobilization and the necessity of their stabi
lization within the genome are emphasized. The existing methods of stabilization which involve the deletion
of transposon terminal inverted repeats are described.