|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ЦЭМИ РАН |
||
GLYCOSYLATED ALPHA-CHYMOTRYPSIN IN REVERSED MICELLES OF AEROSOL-OT IN OCTANE AS A MODEL IN STUDYING THE ROLE OF CARBOHYDRATE FRAGMENTS IN GLYCOPROTEINSстатья
Информация о цитировании статьи получена из
Web of Science
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 29 мая 2015 г.
- Авторы: RARIY RV, KLYACHKO NL, MARTINEK K., LEVASHOV AV
- Журнал: Bioorganicheskaya Khimiya
- Том: 20
- Номер: 3
- Год издания: 1994
- Издательство: Izdatel'stva Nauka
- Местоположение издательства: Russian Federation
- Первая страница: 249
- Последняя страница: 256
- Аннотация: A comparative study of the well known non-glycosylated enzyme alpha-chymotrypsin, and its derivative artificially glycosylated with D-glucosamine was carried out to reveale the effect of carbohydrate fragments on oligomeric composition and membrane activity of glycoproteins. A microheterogeneous system of reversed micelles of Aerosol OT in octane, which can be a model of the biomembrane environment of enzymes in vivo, was used as a medium for enzymatic reactions. It was found that the glycosylation of alpha-chymotrypsin makes the protein to be enables to oligomerization and interaction with the micellar matrix (membrane affinity).
- Добавил в систему: Клячко Наталья Львовна