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Relationship between structure and function of liver mitochondria from hibernating and active ground squirrels, Citellus undulatusстатья
Информация о цитировании статьи получена из
Web of Science
Дата последнего поиска статьи во внешних источниках: 27 мая 2015 г.
- Авторы: Brustovetsky N.N., Egorova M.V., Iljasova E.N., Bakeeva L.E.
- Журнал: Comparative biochemistry and physiology
- Том: 106
- Номер: 1
- Год издания: 1993
- Издательство: Pergamon Press
- Местоположение издательства: United States
- Первая страница: 125
- Последняя страница: 130
- Аннотация: 1. Electron microscopy of liver tissue preparations, obtained from hibernating ground squirrels, reveals mitochondria in a condensed state. 2. When kept on ice, mitochondria isolated from the livers of hibernating and active ground squirrels are in a shrunken state. 3. Incubation of mitochondria isolated from the livers of active ground squirrels in the presence of succinate, at 27 degrees C, results in mitochondrial swelling, while mitochondria from hibernating ground squirrels under the same conditions remain relatively shrunken. 4. The swollen mitochondria from active ground squirrels show high oxidative activity, while the shrunken mitochondria from hibernating animals show low oxidative activity. 5. Swelling of mitochondria from hibernating ground squirrels in a hypo-osmolar medium is accompanied by a significant increase in oxidative activity. 6. It is inferred that the shrinkage of hibernating ground squirrel mitochondria is one of the main causes of the inhibition of oxidative activity and other mitochondrial functions during hibernation.
- Добавил в систему: Бакеева Лора Евгеньевна