Role of ATP as a sympathetic nervous system transmitter in the smoothing of rapid arterial pressure changesстатья
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Дата последнего поиска статьи во внешних источниках: 18 июля 2013 г.
Аннотация:Arterial pressure lability and its variations were examined in unrestrained rats following selective elimination of adrenergic or purinergic sympathetic influences on the circulatory system. Both the alpha(1)-adrenoceptor blocker prazosin and the nonselective alpha-adrenoceptor blocker phentolamine lowered the arterial pressure without affecting its lability. When P-2x purine receptors were desensitized with alpha,beta-methyleneATP, the resulting pronounced hypotension was accompanied by a two-fold increase in the lability of mean arterial pressure.