The participation of brain noradrenergic structures in thermoregulation duringcold adaptationстатья
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Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 28 мая 2015 г.
Местоположение издательства:Leningrad, Russia (Federation)
Первая страница:523
Последняя страница:527
Аннотация:Noradrenaline injected into cerebral lateral ventricles was found to change the
temperature homeostasis in white rats. The fall of rectal temperature, the rise
of brown adipose tissue temperature and oxygen consumption occurred within 25-30
min after the injection. Preliminary adaptation to cold increased the effect of
noradrenaline. The beta-adrenergic blockade of cerebral structures by propranolol
altered the noradrenaline effect: both the rise of brown adipose tissue
temperature and the oxygen consumption increase do not occur. This effect is more
obvious in cold-adapted animals. The adaptation to cold seems to increase the
sensitivity of central adrenergic structures to noradrenaline, central
beta-adrenoreceptors being mainly responsible for the effect of noradrenaline
(the rise of brown adipose tissue temperature and the oxygen consumption
increase) on the thermoregulation.