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[Role of individual lysine residues of horse cytochrome c in the formation of reactive complexes with components of the respiratory chain]статья
Информация о цитировании статьи получена из
Scopus
Дата последнего поиска статьи во внешних источниках: 28 мая 2015 г.
- Авторы: Pepelina T.I.u, Chertkova R.V., Dolgikh D.A., Kirpichnikov M.P.
- Журнал: Bioorganicheskaia khimiia
- Том: 36
- Номер: 1
- Год издания: 2010
- Первая страница: 98
- Последняя страница: 104
- Аннотация: A number of mutant forms of horse cytochrome-c with single or double substitutions of lysine residues near the heme cavity was prepared that provided an interaction of mitochondrial ubiquinone with cytochrome-c reductase (EC 1.10.2.2) (complex III) and cytochrome-c oxidase (EC 1.9.3.1) (complex IV). The succinate cytochrome-c reductase and cytochrome-c oxidase activities of mitoplasts of rat liver were measured in the presence of mutant forms of cytochrome-c. The lysine residues in positions 8, 27, 72, 86, and 87 were shown to be the main contribution to the formation of a reactive complex with ubiquinol-cytochrome-c reductase of the respiratory chain, whereas the lysine residues in positions 13, 79, 86, and 87 were predominantly responsible for the formation of a complex with cytochrome-c oxidase.
- Добавил в систему: Долгих Дмитрий Александрович