|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ЦЭМИ РАН |
||
[Cytoplasm to nucleus translocation patterns of different forms of hepatic estrogen receptors]статья
Дата последнего поиска статьи во внешних источниках: 23 января 2020 г.
- Авторы: Mataradze G.D., Kondrat’ev I.a.I.u, Gontar’ E.V., Smirnov A.N., Rozen V.B.
- Журнал: Biulleten' eksperimental'no∎ biologii i meditsiny
- Том: 91
- Номер: 5
- Год издания: 1981
- Издательство: Administrativnoia Zdaniia Minzdrava Sssr
- Местоположение издательства: Moskva, Russia (Federation)
- Первая страница: 568
- Последняя страница: 571
- Аннотация: Interaction between cell nuclei and the complexes of estradiol (E2) with uterine cytosol estrogen receptors (ER) or with different forms of female and male rat liver cytosol ER was studied and compared. The complexes of E2 with forms I and II of liver ER are capable to translocate to the cell nuclei similarly to E2 receptor complexes of the uterus. The complexes of E2 with an unusual male rat liver estrogen-binding protein do not bind to the nuclei. The processes of translocation of the complexes of E2 with form I of liver ER and uterine receptors have some features in common. In the conditions of low ionic strength media, the complexes of E2 with forms I and II of liver ER manifest differences in the kinetics and level of translocation into the cell nuclei. The differences disappearing with ionic strength increase. The differences disappearing with ionic strength increase. It is suggested that the different forms of liver ER participate in the realization of E2 multiple effects in the liver.
- Добавил в систему: Смирнов Александр Николаевич