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Stereolithographic 3D Printing of Bioceramic Scaffolds of a Given Shape and Architecture for Bone Tissue Regenerationстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 23 сентября 2021 г.
- Авторы: Putlyaev V.I., Yevdokimov P.V., Mamonov S.A., Zorin V.N., Klimashina E.S., Rodin I.A., Safronova T.V., Garshev A.V.
- Журнал: Inorganic Materials: Applied Research
- Том: 10
- Номер: 5
- Год издания: 2019
- Первая страница: 1101
- Последняя страница: 1108
- DOI: 10.1134/s2075113319050277
- Аннотация: A standard series of ceramic scaffolds for bone tissue regeneration with Kelvin architecture wasdeveloped, providing matrix water permeability not less than 900 Darcy and relative rigidity of matrices of notmore than 0.2. The possibility of producing bioceramic scaffolds is shown using stereolithographic 3D printing of light-cured slurries containing a mixed calcium sodium phosphate Ca2.5Na(PO4)2 composition. A production technology of bioceramic scaffolds is developed and tested, including the development of photocurable slurries; 3D printing modes are also worked out, as well as conditions of heat treatment of printed modelsand sintering. The proposed methods of stereolithography formation followed by heat treatment of printedmodels make it possible to produce ceramic scaffolds with lateral resolution no worse than 50 μm and 50 μmlayering. The dimensions of the bioceramic scaffold differ from the reference dimensions of the initial modelby no more than 10%; the degree of macroporosity is not less than 70% and the pore size is 500 μm. It isshown that the obtained bioceramic scaffolds are compatible with the human fibroblast cell culture, are notcytotoxic, do not contain components inhibiting fibroblast adhesion, spreading, and proliferation, and canbe used in tissue engineering.Keywords: bioceramics, calcium phosphates, stereolithography 3D printing, macropores, osteoconductivity,Kelvin structure
- Добавил в систему: Сафронова Татьяна Викторовна
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