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Synthesis and antifungal activity of new hybrids thiazolo[4,5-d]pyrimidines with (1H-1,2,4)triazoleстатья Исследовательская статья
- Авторы: Blokhina Svetlana V., Sharapova Angelica V., Ol'khovich Marina V., Doroshenko Irina A., Levshin Igor B., Perlovich German L.
- Журнал: Bioorganic and Medicinal Chemistry Letters
- Год издания: 2021
- Издательство: Pergamon Press Ltd.
- Местоположение издательства: United Kingdom
- DOI: 10.1016/j.bmcl.2021.127944
- Аннотация: Synthesis and antifungal activity of hybrids of thiazolo[4,5-d]pyrimidines with (1H1,2,4)triazoles are presented. The solubility and lipophilicity of compounds was assessed and itwas discovered that compounds with piperazine linker exhibited significant antifungal activityagainst filamentous and yeast fungi.
- Добавил в систему: Дорошенко Ирина Андреевна