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REPERTOIRE OF REARRANGED IMMUNOGLOBULIN HEAVY CHAIN GENES IN RUSSIAN PATIENTS WITH B-CELL LYMPHOPROLIFERATIVE DISEASESстатья
- Авторы: Biderman B.V., Likold E.B., Smirnova S.Yu, Nikitin E.A., Koroleva D.A., Zvonkov E.E., Al-Radi L.S., Julhakyan H.L., Sudarikov A.B.
- Журнал: CLINICAL LYMPHOMA MYELOMA & LEUKEMIA
- Год издания: 2021
- DOI: 10.1016/j.clml.2021.07.005
- Аннотация: The narrowing of the immunoglobulin heavy chain variable region (IGHV) gene repertoire is a feature of chronic lymphocytic leukemia (CLL) and several other B-cell malignancies. In this study we examined the IGHV gene sequences of 1937 patients with the most common B-cell lymphomas. We present a detailed comparison of B-cell receptor gene repertoires between CLL and other malignancies in patients from Russia and other populations.
- Добавил в систему: Судариков Андрей Борисович