Matrix metalloproteinases 2, 7, and 9 in tumors and sera of patients with breast cancerстатья
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Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 23 сентября 2021 г.
Авторы:
Katunina A.I. ,
Gershtein E.S. ,
Ermilova V.D. ,
Tereshkina I.V. ,
Nazarenko A.Yu,
Tyleuova A.A. ,
Dvorova E.K. ,
Karabekova Z.K. ,
Gritskevich M.V. ,
Berezov T.T.
Журнал:
Bulletin of Experimental Biology and Medicine
Том:
151
Номер:
3
Год издания:
2011
Издательство:
Springer Nature
Местоположение издательства:
Switzerland
Первая страница:
359
Последняя страница:
362
DOI:
10.1007/s10517-011-1330-z
Аннотация:
Enzyme immunoassay showed that the content of matrix metalloproteinases (MMP) 2 and 7 in tumors was higher than in the adjacent histologically intact tissue in 91 and 76% patients with breast cancer, respectively, while MMP-9 levels in the tumor and intact tissue were virtually the same. Serum concentrations of MMP-2 and MMP-7 did not correlate with their levels in the tumors, were within the normal range, and virtually did not decrease after removal of the primary tumor. Serum levels of MMP-9 in patients were significantly lower than in the control and increased after surgery in 85% patients. No clear-cut relationship between the studied parameters and clinical morphological prognostic factors of breast cancer was detected. В© 2011 Springer Science+Business Media, Inc.
Добавил в систему:
Герштейн Елена Сергеевна