Аннотация:The purpose of the research is to analyze the susceptibility of Russia’s multicultural regions to the risks of socioeconomic development and to develop a risk model of state management of this development. It is determined that most negative changes of the values of the indicators of socioeconomic development in top-5 multicultural regions of Russia in 2011–2018 took place at the same time. It is substantiated that multicultural region is susceptible to increased risk of emergence of social and economic crises. That is why the model of state management of the risks of multicultural region’s socioeconomic development should be proactive.