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Multiplexed Analysis of Serum Breast and Ovarian Cancer Markers by Means of Suspension Bead-quantum Dot Microarraysстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Дата последнего поиска статьи во внешних источниках: 4 марта 2022 г.
- Авторы: Brazhnik K., Sokolova Z., Baryshnikova M., Bilan R., Nabiev I., Sukhanova A.
- Сборник: Physics Procedia
- Том: 73
- Год издания: 2015
- Издательство: Elsevier Inc.
- Местоположение издательства: США
- Первая страница: 235
- Последняя страница: 240
- DOI: 10.1016/j.phpro.2015.09.163
- Аннотация: Multiplexed analysis of cancer markers is crucial for early tumor diagnosis and screening. We have designed lab-on-a-bead microarray for quantitative detection of three breast cancer markers in human serum. Quantum dots were used as bead-bound fluorescent tags for identifying each marker by means of flow cytometry. Antigen-specific beads reliably detected CA 15-3, CEA, and CA 125 in serum samples, providing clear discrimination between the samples with respect to the antigen levels. The novel microarray is advantageous over the routine single-analyte ones due to the simultaneous detection of various markers. Therefore the developed microarray is a promising tool for serum tumor marker profiling. © 2015 The Authors.
- Добавил в систему: Барышникова Мария Анатольевна