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The prospect of the creation of a dosage form of domestic analogue of hypothalamic hormonesomatostatin in the treatment of hormone-dependent tumorsстатья
Информация о цитировании статьи получена из
Scopus
Дата последнего поиска статьи во внешних источниках: 20 апреля 2022 г.
- Авторы: Sanarova E.V., Lantsova A.V., Mikhaevich E.I., Shprakh Z.S., Smirnova L.I., Yavorskaya N.P., Oborotova N.A.
- Журнал: Russian Journal of Biopharmaceuticals
- Том: 8
- Номер: 2
- Год издания: 2016
- Первая страница: 13
- Последняя страница: 18
- Аннотация: Hypothalamic peptide hormone — somatostatin — has a broad spectrum of activity, particularly through direct and indirect mechanism antiproliferative effect allows its use as an effective antitumor agent. However, the extreme instability of this substance in the body requires the creation of stable synthetic analogues possessing similar to the natural hormone therapeutic activity. Creation of new somatostatin analogues, the study of their mechanism of action and spectrum of antiproliferative activity and the development of dosage forms is promising areas of modern science.
- Добавил в систему: Санарова Екатерина Викторовна