Colloidochemical Aspects of Transdermal Drug Delivery (Review)статья
Информация о цитировании статьи получена из
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Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 24 декабря 2013 г.
Аннотация:This review generalizes scientific information on factors that determine the efficacy of transdermal drug delivery, including the barrier functions of skin, the properties of drugs and enhancers of skin permeability, and the type of a transdermal therapeutic system, i.e., plaster. Colloidochemical aspects of transdermal drug delivery are considered in relation to the amphiphilic structure of drugs and action mechanisms of enhancers, among which nonionic surfactants prevail. Advantages of microreservoirtype transdermal therapeutic systems are shown, information on which is very scarce; the prospects of their development on the basis of oilinwater and waterinoil emulsions containing nonionic surfactants and polymer adhesives are outlined.