The prevalence of high and low risk human papillomaviruses in the Russian Federation

Faizuloev, E.B.; Kaira, A.N.; Uzbekov, T.R.; Poromov, A.A.; Volynskaya, E.A.; Svitich, O.A.; Zverev, V.V.

Авторы: Faizuloev E.B., Kaira A.N., Uzbekov T.R., Poromov A.A., Volynskaya E.A., Svitich O.A., Zverev V.V.
Журнал: Molecular Genetics, Microbiology and Virology
Том: 39
Номер: 4
Год издания: 2021
Издательство: Allerton Press Inc.
Местоположение издательства: United States
Первая страница: 39
Последняя страница: 47
DOI: 10.17116/molgen20213904139
Аннотация: The aim of the study was to assess the prevalence of high-risk and low-risk human papillomaviruses (HPV) types in the Russian Federation. Materials and methods. Clinical samples (urogenital swabs) were obtained during 2019 from patients with suspected HPV urogenital infection of different sex and ages living in different regions of the Russian Federation (n=12 945). HPV genotyping was performed using the real-time PCR kit QUANT-21 («DNA-Technology», Russia), which allows differential detection of high-risk HPV types 31, 35, 52, 33, 68, 45, 82, 51, 39, 58, 66, 26, 53, 59, 56, 73, 16, 18 and low-risk HPV types 6, 11 and 44. Results. In clinical samples of 5013 patients, 8593 HPV-types were detected (mono infection - in 3057 patients, mixed infection - in 1956 patients). It was shown that on the Russian Federation, the dominant HPV-types are HPV16 - 13.8% (95% CI 13.0-14.5), HPV6 - 10.7% (10.0-11.3), HPV51 - 6.8% (6.3-7.3), HPV44 - 6.8% (6.2-7.3), HPV53 - 6.3% (5.8-6.8), HPV31 - 5.6% (5.2-6.2), HPV56 - 5.5% (5.0-6.0), HPV52 - 5.4% (5.0-5.9), while the percentage of other types varied from 5 to 0.4%. Age, gender, and regional distribution of different HPV types were described. Conclusion. The monitoring of circulating HPV strains will allow predicting the effectiveness of HPV vaccines of various compositions in the Russian Federation, and is of interest in the development of domestic HPV vaccines.
Добавил в систему: Поромов Артем Андреевич

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The prevalence of high and low risk human papillomaviruses in the Russian Federationстатья

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