Аннотация:The article presents modern approaches to the concept of “interdisciplinary integration” in the national and foreign pedagogy, in accordance with which the conceptual series of research is built. The experience of interdisciplinary integration using in the national school is given, its positive and negative sides are revealed. The issues of implementation of interdisciplinary integration in the comprehensive school and in higher educational institutions (high school) that are relevant for modern practice are noted. The authors indicate influence of the newest information technologies, the didactic possibilities of digital educational resources on interdisciplinary interaction. The novelty of the study lies in the fact that interdisciplinary integration is considered in conjunction with school - university (college). The results of the survey of university professors and school teachers are given, which allow teachers to understand the essence of interdisciplinary integration, as well as its level of dissemination in school practice, goals and methods of the interdisciplinary integration using. The survey was attended by teachers from several regions, urban and rural schools. Negative aspects of this process at school level are the following: precision differentiation in integration by cycles (social and humanitarian disciplines, natural- science); lack of integration of different kinds of activity; transfer activity methods from subject to subject; absence of tasks for real-life situations involving the synthesis of knowledge and skills from school practice and social experience of schoolchildren. The study showed that the actualization of educational content through interdisciplinary integration is associated with innovative forms and methods of integration.