Controlled localization of magnetic nanoparticle mechanical activation in suspension exposed to alternating magnetic field using gradient magnetic fieldстатья
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Аннотация:Y. I. Golovin, A.O. Zhigachev, N.L. Klyachko, D.Y. Golovin (2022). Controlled localization of magnetic nanoparticle mechanical activation in suspension exposed to alternating magnetic field using gradient magnetic field. J. Nanopart. Res. V. 24. Art. 167. P. 1-8. Published online: 09 August 2022.https://doi.org/10.1007/s11051-022-05501-8In the past decade, nano-magnetomechanical actuation of biochemical systems for control of their properties on molecular level by means of magnetic nanoparticles in non-heating magnetic fields with frequency below 1 kHz has emerged as distinct branch in nanobiomedicine. From the fundamental point of view, nano-magnetomechanical actuation can provide molecular level locality and specificity; however, non-uniformity and instability of magnetic nanoparticle distribution within the living organism can become the source of unexpected side effects. The present work describes an advantageous physical method of nano-magnetomechanical actuation localization inside the macroscopic area with adjustable volume utilizing gradient magnetic field. Important spatial aspects of such method are considered.