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Post-Traumatic Stress Disorder: Theoretical Approaches and Animal Modelsстатья
- Авторы: Toropova K.A., Ivashkina O.I., Anokhin K.V.
- Журнал: Neuroscience and Behavioral Physiology
- Том: 52
- Номер: 5
- Год издания: 2022
- Издательство: Kluwer Academic/Plenum Publishers
- Местоположение издательства: United States
- Первая страница: 705
- Последняя страница: 721
- DOI: 10.1007/s11055-022-01296-2
- Аннотация: Post-traumatic stress disorder (PTSD) is defined by the International Classification as impairments to emotional state and reactions to a stressful situation in humans. the symptoms of PTSD include anxiety and intrusive memories of the traumatizing event, nightmares, irritability, increased awareness of danger or preoccupation with potential danger, impaired attention, and emotional blunting. The cause of PTSD is an acute psychological trauma induced by a powerful stress-inducing event such as participation in military combat or being in a military combat zone, terrorist acts, natural or technogenic catastrophes, domestic or sexual violence, and the sudden death of a close person, or even health problems. The mechanisms of PTSD have in recent years attracted ever more research attention. Despite great advances in studies of PTSD at the behavioral and psychological, as well as the physiological level, in humans and in a large number of models of PTSD in laboratory animals, the phenomenon of post-traumatic stress disorder remains poorly understood at the theoretical level. This article reviews current concepts of the mechanisms by which PTSD develops, theoretical approaches to understanding this disorder, and experimental data supporting these models.
- Добавил в систему: Ивашкина Ольга Игоревна