|
ИСТИНА |
Войти в систему Регистрация |
ИСТИНА ЦЭМИ РАН |
||
Neurophysiological Aspects of Multiple Hippocampal Transection in Temporal Epilepsyстатья
- Авторы: Kozlova A.B., Korsakova M.B., Pitskhelauri D.I., Kudieva E.S., Dombaanai B.S., Vlasov P.A., Kamenetskaya M.I.
- Журнал: Neuroscience and Behavioral Physiology
- Том: 52
- Номер: 6
- Год издания: 2022
- Издательство: Kluwer Academic/Plenum Publishers
- Местоположение издательства: United States
- Первая страница: 842
- Последняя страница: 848
- DOI: 10.1007/s11055-022-01305-4
- Аннотация: Objectives. To establish a correlation between intraoperative electrocorticography data and seizure monitoring after multiple hippocampal transection in patients with drug-resistant symptomatic medial temporal epilepsy. Results. Control of seizures was achieved in five of the six patients. After transection, synchronized epileptiform activity in the hippocampus disappeared in all cases. Complete disappearance of epileptiform activity in the hippocampus and basal and lateral cortex was achieved in two cases. Epileptiformactivity was seen in the basal cortex in three patients after hippocampal transection. Conclusions. Multiple hippocampal transection provided the opportunity to achieve cessation of synchronized spike activity in the hippocampus in all patients. This correlated with establishment of seizure control in fi ve of the six cases.Persistence and even onset of nonlocalized spike activity in the basal cortex of the temporal lobe had no effect on achievement of seizure control after complete resection of the epileptogenic substrate in the temporal lobe and hippocampal transection. Decreases in the index of epileptiform activity on the scalp EEG were seen mainly by the stage immediately after removal of the pathological substrate, uncus, and amygdalain four of the fi ve cases with baseline epileptiform activity.
- Добавил в систему: Козлова Антонина Борисовна