Аннотация:The aim of this study was to investigate the levels of antioxidant trace elements (zinc, n) and the activity of related metalloenzymes (superoxide dismutase: SOD and glutathione 3Px) in the blood of rabbits experimentally infected with Eimeria stiedae. The results showed Se and serum Zn concentrations, the GPx activity were significantly decreased, serum Cu and blood Cu/ZnSOD activity were increased. As shown in our data the levels of trace : Zn, Cu and Se and the activity of metallo-enzymes CuZnSOD and GPx were significantly changed.Trace elements and related metalloenzymes play a vital role in maintaining the antioxidant sysstem during eimeriosis. The importance of the distribution of trace elements used for antioxidant enzyme synthesis should be in account in the therapeutic support of the parasitized animals, to adjust the nutritional ration to their specific needs and to propose nutritional support recommendation.