Synthesis of Radioiodinated Compounds. Classical Approaches and Achievements of Recent Years

Авторы: Petrov Stanislav A., Yusubov Mekhman S., Beloglazkina Elena K., Nenajdenko Valentine G.
Журнал: International Journal of Molecular Sciences
Том: 23
Номер: 22
Год издания: 2022
Издательство: MDPI
Местоположение издательства: Basel, Switzerland
Номер статьи: 13789
DOI: 10.3390/ijms232213789
Аннотация: This review demonstrates the progress in the synthesis of radioiodinated compounds over the past decade. The possibilities and limitations of radiopharmaceuticals with different iodine isotopes, as well as the synthesis of low and high molecular weight compounds containing radioiodine, are discussed. An analysis of synthesis strategies, substrate frameworks, isolation methods, and metabolic stability, and the possibility of industrial production of radioiodinated organic derivatives which can find applications in the synthesis of drugs and diagnostics are presented.
Добавил в систему: Белоглазкина Елена Кимовна

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