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Changes in intrinsic brain connectivity after a short course of anti-spastic SCS-therapy in patients with left hemisphere brain damage: a pilot studyстатья
- Авторы: Mayorova L.A., Radutnaya M.L., Vorobyev A.N., Puzin K.M., Varyukhina M.D., Petrova M.V., Grechko A.V.
- Сборник: Late Breaking Abstracts
- Серия: 2022
- Том: 17
- Год издания: 2022
- Издательство: SAGE Publications
- Местоположение издательства: United States
- Первая страница: 289
- Последняя страница: 325
- Номер статьи: LB047/1277
- DOI: 10.1177/17474930221128746
- Аннотация: Spasticity is considered a ‘positive’ sign of upper motor neuron syndrome, which occurs after central nervous system damage and manifests as a velocity-dependent increase in resistance during the passive stretch, resulting from hyperexcitability of the stretch reflex. The weakening of the inhibitory influence of the motor cortex, on the spinal α-motoneuron via the brainstem originating lateral reticulospi-nal tract seems to play a crucial role in spasticity occurrence. Evidence suggests that spinal cord stimulation (SCS) may be effective in reducing spasticity. The present pilot study aims to examine whether resting-state functional connectivity (RS-FC) modifies after a short course (1-7 days) of SCS-therapy in patients with left-sided brain damage (due to stroke and TBI) and whether these changes are related to improved regulation of stretch reflex as assessed by the Ashworth scale (AS).
- Добавил в систему: Радутная Маргарита Леонидовна