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Wip1 inhibition leads to severe pro-inflammatory phenotype in skin in response to chemical irritationстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Grigorash Bogdan B., Uyanik Burhan, Kochetkova Elena Y., Goloudina Anastasia R., Demidov Oleg N.
- Журнал: Journal of Dermatological Science
- Год издания: 2017
- Издательство: Elsevier BV
- Местоположение издательства: Netherlands
- DOI: 10.1016/j.jdermsci.2017.03.021
- Аннотация: The stress response in epithelium is particularly important because epithelial tissues in many cases serve as a barrier between the internal milieu and sometime hostile external environment and experience more severe insults compared to other tissues. Wip1 phosphatase as a regulator of several stress signaling pathways such as MAP kinases, DNA damage response, is involved in homeostasis of epithelial tissues and implicated in several pathologies (for review, see [1]). Previously, we have shown that Wip1 plays a critical role in regulation of stress response and tumorigenesis in intestinal epithelium [2,3].
- Добавил в систему: Григораш Богдан Богданович