Diversity and Evolution of Mitochondrial Translation Apparatus

Baleva, M.V.; Piunova, U.E.; Chicherin, I.V.; Levitskii, S.A.; Kamenski, P.A.

Авторы: Baleva Mariya V., Piunova Ulyana E., Chicherin Ivan V., Levitskii Sergey A., Kamenski Piotr A.
Журнал: Biochemistry (Moscow)
Том: 88
Номер: 11
Год издания: 2023
Издательство: Pleiades Publishing, Ltd
Местоположение издательства: Road Town, United Kingdom
Первая страница: 1832
Последняя страница: 1843
DOI: 10.1134/s0006297923110135
Аннотация: The evolution of mitochondria has proceeded independently in different eukaryotic lines, which is reflected in the diversity of mitochondrial genomes and mechanisms of their expression in eukaryotic species. Mitochondria have lost most of bacterial ancestor genes by transferring them to the nucleus or eliminating them. However, mitochondria of almost all eukaryotic cells still retain relatively small genomes, as well as their replication, transcription, and translation apparatuses. The dependence on the nuclear genome, specific features of mitochondrial transcripts, and synthesis of highly hydrophobic membrane proteins in the mitochondria have led to significant changes in the translation apparatus inherited from the bacterial ancestor, which retained the basic structure necessary for protein synthesis but became more specialized and labile. In this review, we discuss specific properties of translation initiation in the mitochondria and how the evolution of mitochondria affected the functions of main factors initiating protein biosynthesis in these organelles.
Добавил в систему: Каменский Петр Андреевич

	ИСТИНА	Войти в систему Регистрация
	ИСТИНА ЦЭМИ РАН
	Главная Поиск Статистика О проекте Помощь

ИСТИНА

ИСТИНА ЦЭМИ РАН

Diversity and Evolution of Mitochondrial Translation Apparatusстатья Исследовательская статья

Прикрепленные файлы