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The Application of Mathematical Modeling Tools in Optimizing the Purification Process of the Substance Oligohexamethyleneguanidine Hydrocitrateстатья
Информация о цитировании статьи получена из
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 26 января 2024 г.
- Авторы: Shatalov Denis, Trachuk Kirill, Aydakova Anna, Akhmedova Diana, Ivanov Ivan, Minenkov Dmitriy, Blazhevich Igor, Kirillova Daria, Kedik Stanislav
- Журнал: Periodica Polytechnica: Chemical Engineering
- Том: 67
- Номер: 2
- Год издания: 2023
- Издательство: Budapesti Muszaki es Gazdasagtudomanyi Egyetem/Budapest University of Technology and Economics
- Местоположение издательства: Hungary
- Первая страница: 287
- Последняя страница: 295
- DOI: 10.3311/ppch.21380
- Аннотация: The current investigation is dedicated to the use of mathematical modeling, particularly the method of multifactorial analysis of multi-criteria optimization (MAMO) in pharmaceutical development. During the investigation the algorithmic sequence was offered and the necessary tests were provided. The gained data was interpreted through MAMO. The possibility of using the MAMO for solving the applied problem of purifying the oligohexamethyleneguanidine hydrocitrate (OHMG-HC) that is considered to be as a pharmaceutical substance for formation of medicines. The dependencies of purifying conditions that have influence on the final impurities contents and the reasonability of using the suggested algorithm as a means of pharmaceutical development.
- Добавил в систему: Миненков Дмитрий Сергеевич