Аннотация:The technical characteristics of the new three models of diffusion-cooled multichannel waveguide industrial CO2 lasers excited with acoustic-frequency ac discharge are presented. The industrial lasers of this type have been developed for years at ILIT RAS. Generation of low (to 400 W) average power proved to be technically realizable through air cooling of the oscillator, which makes the laser performance even more attractive. The above lasers can be used to advantage in the laser processing systems intended for precision cutting of metallic (thickness to 10 mm) and non-metallic (thickness to 40 mm) materials; welding; surfacing and fabrication of parts from composite and metallic powder materials. The paper also provides the description and the technical characteristics of intellectual medical cardio-surgery laser systems of "Perfocor" family, developed at ILIT RAS for the transmyocardial laser revascularization (TMLR) which presents a promising method to cure the ischemic disease of heart. The clinical results (more than 800 operations) are presented. Owing to application of the TMLR technique the death rate at the A.N. Bakoulev Center is the lowest in the world. The project of a new CO2 laser surgery plant "Khirurg" is discussed that would deliver up to 200 W power and is based on the model TL-300 with a system of biotissue diagnostics.