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Nanoparticles prepared from porous silicon nanowires for bio-imaging and sonodynamic therapyстатья
Статья опубликована в высокорейтинговом журнале
Статья опубликована в журнале из списка Web of Science и/или Scopus- Авторы: Osminkina Liubov A., Sivakov Vladimir A., Mysov Grigory A., Georgobiany Veronika A., Natashina Ulyana A., Florian Talkenberg, Solovyev Valery V., Kudryavtsev Andrew A., Timoshenko Victor Yu
- Журнал: Nanoscale Research Letters
- Том: 9
- Номер: 463
- Год издания: 2014
- Издательство: Springer Verlag
- Местоположение издательства: Germany
- DOI: 10.1186/1556-276X-9-463
- Аннотация: Evaluation of cytotoxicity, photoluminescence, bio-imaging, and sonosensitizing properties of silicon nanoparticles (SiNPs) prepared by ultrasound grinding of porous silicon nanowires (SiNWs) have been investigated. SiNWs were formed by metal (silver)-assisted wet chemical etching of heavily boron-doped (100)-oriented single crystalline silicon wafers. The prepared SiNWs and aqueous suspensions of SiNPs exhibit efficient room temperature photoluminescence (PL) in the spectral region of 600 to 1,000 nm that is explained by the radiative recombination of excitons confined in small silicon nanocrystals, from which SiNWs and SiNPs consist of. On the one hand, in vitro studies have demonstrated low cytotoxicity of SiNPs and possibilities of their bio-imaging applications. On the other hand, it has been found that SiNPs can act as efficient sensitizers of ultrasound-induced suppression of the viability of Hep-2 cancer cells.
- Добавил в систему: Осминкина Любовь Андреевна