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Therapeutic Effects of Bacteroides fragilis Vesicles in a Model of Chemically Induced Colitis in Ratsстатья
- Авторы: Shagaleeva O.Yu, Kashatnikova D.A., Vorobyeva E.A., Kardonsky D.A., Silantiev A.S., Efimov B.A., Ivanov V.A., Bespyatikh Yu A., Zakharzhevskaya N.B.
- Журнал: Bulletin of Experimental Biology and Medicine
- Год издания: 2024
- Издательство: Springer Nature
- Местоположение издательства: Switzerland
- DOI: 10.1007/s10517-024-06237-2
- Аннотация: The anti-inflammatory properties of Bacteroides fragilis vesicles were studied in a rat model of dextran sodium sulfate-induced colitis. According to the histology results, addition of B. fragilis vesicles to the therapy promoted colon repair. Evaluation of the disease activity index confirms the high rate of colon recovery: against the background of vesicle administration, the absence of blood in stool, normal stool consistency, and body weight normalization were observed.
- Добавил в систему: Воробьева Елизавета Андреевна