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Practical Achievements of Laboratory Evolutionстатья
- Авторы: Dunaevsky Ya E., Kudryavtseva O.A., Agroskin S.M., Gasparyan A.A., Belozersky M.A.
- Журнал: Applied Biochemistry and Microbiology
- Том: 60
- Номер: 6
- Год издания: 2024
- Издательство: Maik Nauka/Interperiodica Publishing
- Местоположение издательства: Russian Federation
- Первая страница: 1010
- Последняя страница: 1021
- DOI: 10.1134/S000368382460533X
- Аннотация: https://doi.org/10.1134/S000368382460533XAdaptive Laboratory Evolution (ALE) is a novel approach to generating microbial strains with desired characteristics and producing value-added products. Additionally, ALE is employed as a means of enhancing comprehension of the genetic and/or metabolic pathways of evolution. The objective of this review is to analyze the results of studies that elucidate and demonstrate the potential of microorganisms as model objects for laboratory evolutionary experiments. These experiments are becoming increasingly prevalent in the study of adaptation, the evaluation of evolutionary dynamics, and the testing of various evolutionary hypotheses. Concurrently, ALE has demonstrated itself to be a promising and efficacious methodology, which, when employed for biotechnological applications, has already resulted in the generation of novel and useful microbial strains. It is important to note that the current achievements not only demonstrate the power and versatility of this approach but also highlight a number of unanswered questions. The conclusions drawn on the basis of ALE require a cautious interpretation of the results obtained.
- Добавил в систему: Дунаевский Яков Ефимович
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Полный текст | ABM1010.pdf | 514,9 КБ | 27 февраля 2025 [BelozerskyMA] | |
| 2. | заключение.pdf | заключение.pdf | 55,9 КБ | 13 декабря 2024 [Dunaevsky] |