Аннотация:Multi-proxy records from the Meshchera Lowlands (the central part of the East European Plain) lands provide important new information on several large environmental changes that occurred in the central part of the East European Plain during the Holocene. The results of pollen, plant macrofossil, charcoal and testate amoeba analyses showed that vegetation changes were mainly influenced by climate change and fire. Since 8500 cal yr BP, the vegetation history in the region was characterized by a series of consecutive phases of birch, birch-pine and pine-broadleaf forests with participation of spruce after 2500 cal yr BP. The increase in the proportion of broadleaved tree species in the study area occurred later in comparison with other territories of the central part of the East European Plain, probably due to unfavorable soil conditions and frequent fires, which resulted in the persistence of birch and pine forests. The greatest abundance of broadleaf tree species was detected during the period of 4700-2000 cal yr BP. Our data indicated that a reduction in soil moisture during that time favored the growth of broadleaf trees in habitats with hampered drainage conditions. High fire frequency was reconstructed for the periods of 8500-4500 cal yr BP and 3500-2000 cal yr BP, when the fire return interval varied from 40 to 80 years. The reconstructed fire return intervals agreed well with charcoal data from other peatlands in Northern and Central Europe. Around 2000 cal yr BP, cooling and increased climate humidity resulted in a reduction of broadleaf forests and an expansion of spruce in the south-eastern Meshchera Lowlands. Fire frequency decreased during the last two millennia to over 500 years. Human activity increased in the region since 1400 cal yr BP and were largely related to felling trees and agricultural expansion.