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Hepatitis C virus subtype 3a was introduced in the USSR in the early 1980sстатья
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 17 октября 2017 г.
- Авторы: Manuylov VA, Chub EV, Kichatova VS, Soboleva NV, Isaeva OV, Zamyatnin AA Jr, Netesov SV
- Журнал: Journal of General Virology
- Том: 98
- Номер: 8
- Год издания: 2017
- Издательство: Society for General Microbiology
- Местоположение издательства: United Kingdom
- Первая страница: 2079
- Последняя страница: 2087
- DOI: 10.1099/jgv.0.000878
- Аннотация: A total of 2120 nucleotide sequences of the NS5b region of HCV subtype 3a were analysed, including 310 strains derived from former republics of the USSR (Azerbaijan, Estonia, Lithuania, Russia, Tajikistan and Uzbekistan). Among the viral isolates collected from former regions of the Soviet Union, 294 strains formed 3 sustained phylogenetic clusters, with each having a common origin. Phylodynamic analysis demonstrated that the most recent common ancestors of the current strains inside the three clusters were introduced into the USSR population in 1981±1, 1984±2 and 1985±2, respectively (the confidence intervals were calculated using Student's t-distribution, P<0.05). The time estimation obtained for HCV subtype 3a correlated well with the historical and epidemiological context of this period, and in particular with the start of widespread injection drug use in the USSR in the first half of the 1980s.
- Добавил в систему: Замятнин Андрей Александрович
Прикрепленные файлы
| № | Имя | Описание | Имя файла | Размер | Добавлен |
|---|---|---|---|---|---|
| 1. | Полный текст | Manuylov_2017.pdf | 293,6 КБ | 17 октября 2017 [zamyat] |