A General Metal‐Assisted Synthesis of α‐Halo Oxime Ethers from Nitronates and Nitro Compoundsстатья
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Дата последнего поиска статьи во внешних источниках: 19 сентября 2017 г.
Аннотация:An approach to the synthesis of α-halo oxime ethers from readily accessible nitronates and nitro compounds via bis(oxy)enamines is reported. A key step of the strategy involves the unprecedented reaction of bis(oxy)enamines with a metal (Co, Zn, Mg, Mn) halide that acts as both a promoter and halide (Br, I, Cl) source. A variety of cyclic and acyclic ethers of α-halo oximes, including previously unavailable trimethylsilyl ethers of α-iodo oximes, have been synthesized in good-to-high yields.