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Surgical Treatment of the Primary Sinonasal Malignancies with Dural and Brain Involvementстатья Тезисы
Информация о цитировании статьи получена из
Web of Science,
Scopus
Статья опубликована в журнале из списка Web of Science и/или Scopus
Дата последнего поиска статьи во внешних источниках: 23 ноября 2017 г.
- Авторы: Dmitriy Spirin, Viacheslav Nazarov, Islam Muzishev, Vasiliy Cherekaev, Grigoriy Kobyakov, Igor Reshetov, Elena Vetlova, Oksana Absaliamova
- Журнал: Turkish Neurosurgery
- Том: 27
- Год издания: 2017
- Издательство: Turkish Neurosurgical Society
- Местоположение издательства: Turkey
- Первая страница: 516
- Последняя страница: 516
- Аннотация: Experience in treatment of 142 patients with primary sinonasal malignancies with dural and brain involvement in a single institution was performed. Major types of histological diagnoses were: adenocystic cancer, adenocarcinoma, low differentiated carcinoma, sinonasal undifferentiated carcinoma, nasopharyngeal cancer. Tumor initial sites were nasal cavity, paranasal sinuses and nasopharynx. These tumors usually destruct anterior skull base and invade dura and brain tissue. TNM distribution of the tumors was following: T4a (63%) and T4b (37%). Indications for surgery were developed: the removal of intradural tumor mass, cytoreduction, histological verification in the absence of pre-biopsy the tumor. We performed craniofacial resection in 27%, subtotal removal in 25% and biopsy in 48%. The main problems in the surgery planning were highlighted: resection margins, large skull base defect reconstruction, general poor condition of the patient because of the chemotherapy, metastases, respiratory disorders and cachexia. Preoperative algorithm was described: autologous blood harvesting (serum and red blood cells), correction of water-electrolyte and protein metabolic disorders. Complications of craniofacial resection and subtotal removal were pointed: nasal CSF leak (16%), infectious and inflammatory complications (8%), oculomotor and visual impairment (5%), autograft necrosis (4%), and anemia (17%). The mortality rate was 2%. Indications and contraindications for resection of the tumor were developed. Optimal ways of scull base reconstruction after tumor removal were described. Follow-up period was 4 years.
- Добавил в систему: Назаров Вячеслав Вячеславович